1: Genomes and the flow of biological information
2: Biological molecules
3: The chemical basis of life
4: Chromosome structure and function
5: The cell cycle
6: DNA replication
7: Chromosome segregation
9: Regulation of transcription
10: RNA processing
12: Regulation of translation
13: Regulatory RNAs
14: Protein modification and targeting
15: Cellular responses to DNA damage
16: Repair of DNA double-strand breaks and homologous recombination
17: Mobile DNA
18: Genomics and genetic variation
19: Tools and techniques in molecular biology
The biological world operates on a multitude of scales - from molecules to cells to tissues to organisms to ecosystems. Throughout all these levels runs a common thread: the communication and onward passage of information - from cell to cell, from organism to organism and, ultimately, from generation to generation. But how does this information - no more than a static repository of data - come alive to govern the processes that constitute life?
The answer lies in the concerted action of molecular components which cooperate through a series of carefully-regulated processes to bring the information in our genome to life. These components and processes lie at the heart of one of the most fascinating subjects to engage the minds of scientists today: molecular biology.
Molecular Biology: Principles of Genome Function offers a fresh, distinctive approach to the teaching of molecular biology. It is an approach that reflects the challenge of teaching a subject that is in many ways unrecognizable from the molecular biology of the 20th century - a discipline in which our understanding has advanced immeasurably, but about which many questions remain to be answered...