Preface
Acknowledgments
Editors
Contributors
PART I. INTRODUCTION: EPIDEMIOLOGY, SOCIOECONOMIC IMPACT, AND CHALLENGES AHEAD
1. Introduction to virus structure, classification, replication, and hosts
Philippe Simon and Kevin M. Coombs
2. Neuropathogenesis of viral infections
Avindra Nath and Joseph R. Berger
3. An approach to pathogen discovery for viral infections of the nervous system
Prashanth S. Ramachandran and Michael R. Wilson
4. Neuropathology of CNS viral infections and the role of brain biopsy in the diagnosis
Susan Morgello
PART II. DNA VIRUSES
5. Herpes simplex viruses
Israel Steiner and Felix Benninger
6. Varicella zoster virus infection
Don Gilden, Randall J. Cohrs, Dallas Jones, and Maria A. Nagel
7. EpsteinBarr virus and the nervous system
Alexandros C. Tselis, Kumar Rajamani, and Pratik Bhattacharya
8. Cytomegalovirus
Joseph R. Berger
9. Progressive multifocal leukoencephalopathy
Eric M. L. Williamson and Joseph R. Berger
10. Adenovirus
Jennifer McGuire and Joseph R. Berger
PART III. RETROVIRUSES
11. HIV neurological complications
Alessandro Fois and Bruce Brew
12. Human T lymphotropic virus type 1 (HTLV-1)
Shila Azodi and Steven Jacobson
PART IV. RNA VIRUSES
13. Rabies and other lyssaviruses
Thiravat Hemachudha, Jiraporn Laothamatas, and Henry Wilde
14. Neurological manifestations of West Nile virus
Daniel E. Smith, J. David Beckham, Daniel M. Pastula, and Kenneth L. Tyler
15. Chikungunya virus and Japanese encephalitis virus
Jennifer L. Lyons
16. Arthropod-borne virus encephalitis
Joseph R. Berger
17. Enteroviruses
Karen Straube-West and Burk Jubelt
18. Measles and its neurological complications
Benedikt Weissbrich and Jürgen Schneider-Schaulies
19. Rubella
Avindra Nath
20. Influenza neurologic complications
Larry E. Davis and Jennifer R. Plourde
21. Nipah encephalitis, a fatal encephalitis with bats as reservoir
Chong-Tin Tan and Kum-Thong Wong
PART 5. MISCELLANEOUS
22. Von Economos encephalitis
Joseph R. Berger
23. Neurological events following immunizations
James J. Sejvar
24. Central nervous system viral infections complicating immunosuppression
Amy A. Pruitt
25. Post-viral syndromes
Anusha K. Yeshokumar, Eliza Gordon-Lipkin, and Brenda Banwell
26. Viral neuro-oncogenesis: Polyomaviruses and brain tumors
Martyn K. White, Sidney E. Croul, and Kamel Khalili
27. Autoimmune disorders that can be mistaken for viral illness
Maxwell Greene and Eric Lancaster
28. Antiviral therapeutics for viral infections of the central nervous system
Richard Whitley
29. Neurological manifestations of coronavirus infections
Avindra Nath and Joseph R. Berger
Index
This is a comprehensive reference that includes the basic science, clinical features, imaging, pathology and treatment of specific viral entities affecting the central nervous system (CNS). It will assist professionals in their attempt to identify, examine and manage viral CNS infections and unravel the therapeutic and diagnostic challenges associated with viral CNS disorders.
