COSSART, P. / ROY, C. / SANSONETTI, P.
Contributors ix
Preface xv
About the Editors xvii
I. Cellular microbiology in the study of tissue and organ infections
1. Interaction between Intracellular Bacterial Pathogens and Host Cell Mitochondria 3
Anna Spier, Fabrizia Stavru, and Pascale Cossart
2 Shigella Pathogenesis: New Insights through Advanced Methodologies 15
Pamela Schnupf and Philippe J. Sansonetti
3. The Interplay between Salmonella enterica Serovar Typhimurium and the Intestinal Mucosa during Oral Infection 41
Annika Hausmann and Wolf-Dietrich Hardt
4. New Age Strategies To Reconstruct Mucosal Tissue Colonization and Growth in Cell Culture Systems 59
Alyssa C. Fasciano, Joan Mecsas, and Ralph R. Isberg
5. The Many Faces of Bacterium-Endothelium Interactions during Systemic Infections 69
Dorian Obino and Guillaume Duménil
6. Reaching the End of the Line: Urinary Tract Infections 83
Kevin O. Tamadonfar, Natalie S. Omattage, Caitlin N. Spaulding, and Scott J. Hultgren
7. The Intracellular Life Cycle of Brucella spp. 101
Jean Celli
8. Infect and Inject: How Mycobacterium tuberculosis Exploits Its Major Virulence-Associated Type VII Secretion System, ESX-1 113
Sangeeta Tiwari, Rosalyn Casey, Celia W. Goulding, Suzie Hingley-Wilson, and William R. Jacobs, JR.
9. Mycobacterium tuberculosis: Bacterial Fitness within the Host Macrophage 127
Lu Huang, Evgeniya V. Nazarova, and David G. Russell
10. The Wolbachia Endosymbionts 139
Frédéric Landmann
11. Make It a Sweet Home: Responses of Chlamydia trachomatis to the Challenges of an Intravacuolar Lifestyle 155
Sébastien Triboulet and Agathe Subtil
12. Salmonella Single-Cell Metabolism and Stress Responses in Complex Host Tissues 167
Dirk Bumann
13. Manipulation of Host Cell Organelles by Intracellular Pathogens 179
Titilayo O. Omotade and Craig R. Roy
II. Subcellular microbiology
14. The Role of the Type III Secretion System in the Intracellular Lifestyle of Enteric Pathogens 199
Marcela de Souza Santos and Kim Orth
15. Customizing Host Chromatin: A Bacterial Tale 215
Michael Connor, Laurence Arbibe, and Mélanie Hamon
16. Cell Biology of Intracellular Adaptation of Mycobacterium leprae in the Peripheral Nervous System 227
Samuel Hess and Anura Rambukkana
17. Multifaceted Roles of MicroRNAs in Host-Bacterial Pathogen Interaction 247
Carmen Aguilar, Miguel Mano, and Ana Eulalio
18. Modulation of Host Cell Metabolism by Chlamydia trachomatis 267
Marion Rother, Ana Rita Teixeira da Costa, Rike Zietlow, Thomas F. Meyer, and Thomas Rudel
III. Autonomous defense pathways in the cell
19. Host-Encoded Sensors of Bacteria: Our Windows into the Microbial World 279
Charlotte Odendall and Jonathan C. Kagan
20. Recognition of Intracellular Bacteria by Inflammasomes 287
Petr Broz
IV. New technologies to move cellular microbiology to organs and tissues
21. Modeling Infectious Diseases in Mice with a Humanized Immune System 301
Yan Li and James P. di Santo
22. A Cinematic View of Tissue Microbiology in the Live Infected Host 315
Agneta Richter-Dahlfors and Keira Melican
23. Cellular Imaging of Intracellular Bacterial Pathogens 325
Virginie Stévenin and Jost Enninga
24. Using a Systems Biology Approach To Study Host-Pathogen Interactions 337
Amy Yeung, Christine Hale, Simon Clare, Sophie Palmer, Josefin Bartholdson Scott, Stephen Baker, and Gordon Dougan
Index 349
Bacteria and Intracellularity clearly demonstrates that cellular microbiology as a field has reached maturity, extending beyond the strictly cellular level to infections of various organs and tissues. Decades of intense investigation into host-bacterial pathogen interactions have highlighted common concepts in intracellularity but also very diverse mechanisms underlying the various infections produced by bacteria...
